Which Sickness Would You Least Want to Be Infected With?

Over the centuries, many hundreds of millions of people have succumbed to many thousands of various diseases and viruses, especially in the twentieth century. Some proved to be worse than others, and constant mutations, resilience, and resistance provide the human world with new surprises at every twist and turn. Therefore, which sickness would you least want to be infected with? Please share your courageous opinion.